Not all CD20-positive lymphomas are of B cell origin
Dr. Yu-Hung Wu
- The initial screening panel of cutaneous lymphomatous infiltrate often includes CD3 for T cells, CD20 for B cells, and CD30 for large lymphoid cells. The co-existence of both positivity of CD3 and CD20 causes diagnostic challenge. In this presentation, we will demonstrate a double-positive lymphoma and discuss the possible pathogenesis of this phenomenon.
Diagnostic Approach to non-Mycosis Fungoides Cutaneous T-cell Lymphoma
Dr. Shih-Sung Chuang
- Mycosis fungoides is the prototype of primary cutaneous T-cell lymphoma and is more common in the West than in the East, whereas nonmycotic primary cutaneous T-cell lymphoma is more frequent than mycosis fungoides among Asians. Nonmycotic primary cutaneous T-cell lymphomas comprise several categories of neoplasms and might pose diagnostic challenges because of the rarity of these lesions and overlapping features among certain entities. The authors recommend diagnostic approaches including histopathological evaluation, immunohistochemical markers, and ancillary studies. Diagnostic dilemma in certain entities and cases with atypical clinicopathological features are discussed. (J Am Acad Dermatol 2014;70:724-35)
Cutaneous Lymphomas in Immunosuppressed Individuals
Dr. Lorenza Cerroni
- This lecture will cover several cutaneous lymphomas or lymphoproliferative disorder in immunosuppressed individuals. They are cutaneous post-transplant lymphoproliferative disorders, cutaneous lymphomas in HIV-infected individuals, and cutaneous lymphoproliferative disorders in other iatrogenic and non-iatrogenic immune deficiencies.
